The Accelerating Innovation for Mothers (AIM) project – spearheaded by the Concept Foundation and delivered in partnership with Policy Cures Research and Burnet Institute – was created with the aim of fostering greater investment in and development of critical maternal health products for seven significant pregnancy-related conditions, where biomedical product gaps exist: 

  • Preterm labour/birth
  • Preeclampsia/eclampsia
  • Intrauterine growth restriction 
  • Postpartum haemorrhage
  • Intrapartum foetal distress
  • Maternal enteric microbiome/environmental enteric dysfunction
  • Maternal iron deficiency anaemia

As part of this work, Policy Cures Research has created a comprehensive database profiling medicines, diagnostics, and devices – both approved and in the development pipeline – for these seven conditions. These are included in the interactive product pipeline below.  Alternatively, you can download the Excel version here.

The Maternal Health Pipeline includes:

  • medicines for preterm labour/birth, preeclampsia/eclampsia, intrauterine growth restriction, postpartum haemorrhage, intrapartum foetal distress, maternal enteric microbiome/environmental enteric dysfunction, and maternal iron deficiency anaemia.
  • diagnostic tests for preeclampsia/eclampsia, preterm labour and intrauterine growth restriction, and
  • devices for postpartum haemorrhage.

To be included in the pipeline, the medicines, diagnostic tests and devices had to either be in active discovery/pre-clinical or clinical development now, or have been in development at one point between 2000 and 2023, or be approved and registered for clinical use and/or be used currently in clinical treatment (off-label).

We undertook a series of partially sequential, partly overlapping, but mutually reinforcing steps to develop a database of candidate profiles. These were:

  1. Identify and validate candidates through multiple sources that are or were in the pipeline for each of the identified pregnancy-related conditions since 2000;
  2. Collect information on the candidate’s preclinical or clinical development, and associated data;
  3. Research additional context around the product (e.g. development history, stakeholders)
  4. Validate and sense check candidate profiles through independent, external reviews by clinical research specialists in the field.

For a more detailed description of the methodology, see here.

The pipeline of products for seven pregnancy-related conditions