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Analysis

We use the evidence collected through the G-FINDER project and our R&D pipeline tracker to produce a range of independent reports, which you can find below.

G-FINDER – emerging infectious diseases

A new G-FINDER report provides a comprehensive look at R&D to fight emerging infectious diseases (EIDs), covering global funding for WHO priority EIDs between 2014 and 2018. The funding data included in the report covers a range of pathogens with recognised pandemic potential, including coronaviruses, Ebola, Zika, and as-yet-unknown pathogens captured under the heading of ‘Disease X’.

G-FINDER – sexual and reproductive health

A new G-FINDER report presenting the diverse sexual and reproductive health (SRH) R&D funding landscape highlights a broad spectrum of investment in 2018.

Based on responses from governments, non-profits, foundations and industry, the 2020 G-FINDER SRH report provides the most up-to-date comprehensive look at the R&D landscape for SRH health issues that disproportionately affect people in low- and middle-income countries (LMICs).

G-FINDER – neglected diseases

Data on global investment in neglected disease R&D is collected in the G-FINDER survey and published in our annual G-FINDER report. The reports provide up-to-date analysis of how R&D investment is allocated across diseases and product types, funding trends over time, and the location of potential gaps in funding.

The 2019 G-FINDER report covers 36 neglected diseases across a combined total of 160 product areas, including drugs, vaccines, biologics, diagnostics, microbicides, and vector control products, as well as non-disease-specific platform technologies.

For older G-FINDER reports and associated publications produced prior to the separation of Policy Cures Research from Policy Cures, please see here.

G-FINDER Snapshots

Policy Cures Research examines targeted global health product innovations and R&D investment landscapes in our new Snapshot series.

The first 2020 G-Finder Snapshot is Next Generation Chemical Vector Control: Essential Tools in the Battle Against Malaria. The report provides a trend analysis of chemical vector control product (VCP) R&D funding from 2007-2018, a deep dive into the new dual insecticide-treated net (Interceptor G2), and an outlook of the chemical VCP development pipeline (also see press release).

Country profiles

Policy Cures Research publishes country-specific funding profiles based on the data gathered as part of the G-FINDER survey.

G-FINDER 2019 key findings: EU funding of poverty-related and neglected disease R&DThis fact sheet provides a brief summary of the 2018 funding for neglected disease R&D provided by the European Commission, through Horizon 2020 and the European and Developing Countries Clinical Trials Partnership (EDCTP). It breaks down changes in the balance of European Union funding between EDCTP and Horizon 2020 programmes and provides a summary of the allocation of EU funding across individual diseases and stages of R&D.

Global funding for snakebite envenoming research 2007-2018

The findings from Policy Cures Research’s report Global funding for snakebite envenoming research 2007-2018, commissioned by the Wellcome Trust, were presented at the third Snakebites Funders Forum, hosted by the Wellcome Trust in London on 15 November 2019.

The findings explore the results of the first ever survey on global investment of snakebite research, which was conducted as part of this project. The project was based on the G-FINDER survey of neglected disease biomedical R&D, which was expanded to include snakebite-related operational, implementation and health systems and policy research, based on the areas of interest identified by the Wellcome Trust and a panel of independent international experts.

The survey collected 12 years of data (2007 to 2018), allowing for time-series analysis. This report provides an overview of the landscape of researchers active in snakebite envenoming research and explores trends across the 12-year period, highlighting areas of unmet need.

Snakebite envenoming was also included in the G-FINDER survey for neglected diseases for the first time in 2019. Investment in biomedical R&D for snakebite envenoming will continue to be tracked by G-FINDER in future years.

Bridging the gaps in malaria R&D

Policy Cures Research, together with the Foundation for Innovative New Diagnostics, the Innovative Vector Control Consortium, the Medicines for Malaria Venture, and the WHO’s Global Malaria Programme, contributed to this 2018 report developed by Malaria No More UK, PATH and the WHO Special Programme for Research and Training in Tropical Diseases, which looks at global funding for malaria R&D over the last decade, and highlights gaps in financial reporting and monitoring tools to document funding for malaria research for implementation. The report covers findings from a pilot study on malaria research for implementation funding, which includes implementation research, operational research, and health systems research. It highlights the importance of improving coordination across intervention areas, developing more innovative funding approaches and continuing existing tracking of funding flows.

The report expands on an interim PCR publication, released earlier in 2018, titled Investigating a Second Valley of Death in Malaria R&D: How is research for implementation funded? This earlier report focused on the critical role played by implementation research, operational research, and health systems research in both shaping the development of new health technologies so they are designed for the conditions in which they will be used, and ensuring that they are introduced in the right place, at the right time, and in the right quantities.

Return on innovation: A smart investment for the US

Policy Cures Research worked with the Global Health Technologies Coalition to publish a joint report on Return on Innovation in July 2017, examining the return on investment for the United States from its support of global health R&D.

The report explores the investments made and the role played by key US institutions such as the Agency for International Development, the National Institutes of Health, the Department of Defense and the Centers for Disease Control, the achievements made with the help of US investments, and how this investment has contributed to a pipeline of products to address global health needs. The report finds that US government investment of around $14 billion in R&D for global health has been a smart investment, delivering economic and security returns for Americans while playing an essential role as a catalyst for the development of new drugs, vaccines, diagnostics and other urgently-needed tools for fighting neglected disease.

Saving lives: Making the case for European investment in poverty-related and neglected disease R&D

Commissioned by Deutsche Stiftung Weltbevölkerung (DSW), the 2016 Saving Lives report updates a previous 2012 study, analysing how European Union funding for poverty-related and neglected diseases R&D compares with the direct investments made by European governments. The report assesses the impact that this investment has had on global health, and estimates the flow-on economic and employment benefits for Europe.

The European public sector plays a pivotal role in supporting R&D to deliver new tools to combat neglected diseases such as leprosy, diarrhoeal diseases, dengue, helminth infections and trachoma.  In an era in which global public funding for neglected disease R&D is waning, and governments face competing demands for health and R&D budgets, this report provides a timely reminder of why the European contribution matters.